Genes and Development

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

GENES & DEVELOPMENT 4:503-514, 1990
ISSN 0890-9369
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chasman, D I
Right arrow Articles by Kornberg, R D
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chasman, D I
Right arrow Articles by Kornberg, R D
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Research Papers

A yeast protein that influences the chromatin structure of UASG and functions as a powerful auxiliary gene activator.

D I Chasman, N F Lue, A R Buchman, J W LaPointe, Y Lorch, and R D Kornberg

Department of Cell Biology, Fairchild Center, Stanford School of Medicine, California 94305.

Abstract

GRF2, an abundant yeast protein of Mr approximately 127,000, binds to the GAL upstream activating sequence (UASG) and creates a nucleosome-free region of approximately 230 bp. Purified GRF2 binds to sequences found in many other UASs, in the 35S rRNA enhancer, at centromeres, and at telomeres. Although GRF2 stimulates transcription only slightly on its own, it combines with a neighboring weak activator to give as much as a 170-fold enhancement. This effect of GRF2 is strongly distance-dependent, declining by 85% when 22 bp is interposed between the GRF2 and neighboring activator sites.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Mol. Cell. Biol.Home page
A. Yarragudi, T. Miyake, R. Li, and R. H. Morse
Comparison of ABF1 and RAP1 in Chromatin Opening and Transactivator Potentiation in the Budding Yeast Saccharomyces cerevisiae
Mol. Cell. Biol., October 15, 2004; 24(20): 9152 - 9164.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
C. Van Slyke and E. J. Grayhack
The essential transcription factor Reb1p interacts with the CLB2 UAS outside of the G2/M control region
Nucleic Acids Res., August 1, 2003; 31(15): 4597 - 4607.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Angermayr, U. Oechsner, and W. Bandlow
Reb1p-dependent DNA Bending Effects Nucleosome Positioning and Constitutive Transcription at the Yeast Profilin Promoter
J. Biol. Chem., May 9, 2003; 278(20): 17918 - 17926.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
L. M. Ettwiller, J. Rung, and E. Birney
Discovering Novel cis-Regulatory Motifs Using Functional Networks
Genome Res., May 1, 2003; 13(5): 883 - 895.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Angermayr and W. Bandlow
Permanent Nucleosome Exclusion from the Gal4p-inducible Yeast GCY1 Promoter
J. Biol. Chem., March 21, 2003; 278(13): 11026 - 11031.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Fourel, T. Miyake, P.-A. Defossez, R. Li, and E. Gilson
General Regulatory Factors (GRFs) as Genome Partitioners
J. Biol. Chem., October 25, 2002; 277(44): 41736 - 41743.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. M. A. Moreira, W. Horz, and S. Holmberg
Neither Reb1p nor Poly(dA{middle dot}dT) Elements Are Responsible for the Highly Specific Chromatin Organization at the ILV1 Promoter
J. Biol. Chem., January 25, 2002; 277(5): 3202 - 3209.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
B. Ren, F. Robert, J. J. Wyrick, O. Aparicio, E. G. Jennings, I. Simon, J. Zeitlinger, J. Schreiber, N. Hannett, E. Kanin, et al.
Genome-Wide Location and Function of DNA Binding Proteins
Science, December 22, 2000; 290(5500): 2306 - 2309.
[Abstract] [Full Text]

Home page
 Nucleic Acids ResHome page
C. E. Koering, G. Fourel, E. Binet-Brasselet, T. Laroche, F. Klein, and E. Gilson
Identification of high affinity Tbf1p-binding sites within the budding yeast genome
Nucleic Acids Res., July 1, 2000; 28(13): 2519 - 2526.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
L. Yu and R. H. Morse
Chromatin Opening and Transactivator Potentiation by RAP1 in Saccharomyces cerevisiae
Mol. Cell. Biol., August 1, 1999; 19(8): 5279 - 5288.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
K. L.-C. Wang and J. R. Warner
Positive and Negative Autoregulation of REB1 Transcription in Saccharomyces cerevisiae
Mol. Cell. Biol., July 1, 1998; 18(7): 4368 - 4376.
[Abstract] [Full Text]

Home page
 ScienceHome page
M. J. Pazin, P. Bhargava, E. P. Geiduschek, and J. T. Kadonaga
Nucleosome Mobility and the Maintenance of Nucleosome Positioning
Science, May 2, 1997; 276(5313): 809 - 812.
[Abstract] [Full Text]

Home page
 ScienceHome page
R. Morse
Nucleosome disruption by transcription factor binding in yeast
Science, December 3, 1993; 262(5139): 1563 - 1566.
[Abstract] [PDF]

Home page
 Genes Dev.Home page
J D Axelrod, M S Reagan, and J Majors
GAL4 disrupts a repressing nucleosome during activation of GAL1 transcription in vivo.
Genes & Dev., May 1, 1993; 7(5): 857 - 869.
[Abstract] [PDF]

Home page
 Genes Dev.Home page
I C Taylor, J L Workman, T J Schuetz, and R E Kingston
Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains.
Genes & Dev., July 1, 1991; 5(7): 1285 - 1298.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Genome Res. Learn. Mem.
Protein Science RNA Genes Dev.