QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Ruaud, A.-F. Articles by Thummel, C. S. PubMed PubMed Citation Articles by Ruaud, A.-F. Articles by Thummel, C. S. Related Content Neurobiology Signal Transduction Related Article Social Bookmarking                   What's this?

PERSPECTIVE

Serotonin and insulin signaling team up to control growth in Drosophila

Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA

Neuroendocrine signaling pathways play a central role in modulating animal body size in response to environmental signals. Little is known, however, regarding how these neuroendocrine circuits are controlled. An important advance in this area is reported in this issue of Genes & Development by Kaplan and colleagues (pp. 1877–1893), who show that serotonergic neurons regulate the growth of peripheral tissues in Drosophila through the insulin/IGF pathway.

[Keywords: Nucleostemin; serotonin; insulin; neurons; growth; size]

E-MAIL carl.thummel{at}genetics.utah.edu; FAX (801) 581-5374.

Article is online at http://www.genesdev.org/cgi/doi/10.1101/gad.1700708.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

Related Article

A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size

Daniel D. Kaplan, Gregor Zimmermann, Kaye Suyama, Tobias Meyer, and Matthew P. Scott
Genes & Dev. 2008 22: 1877-1893. [Abstract] [Full Text] [PDF]